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Simultaneous parameter mapping, modality synthesis, and anatomical labeling of the brain with MR fingerprinting
Gomez, Pedro A. Molina-Romero, Miguel Ulas, Cagdas Bounincontri, Guido Sperl, Jonathan I. Jones, Derek Menzel, Marion I. Menze, Bjoern H.
Gomez, Pedro A.
Molina-Romero, Miguel
Ulas, Cagdas
Bounincontri, Guido
Sperl, Jonathan I.
Jones, Derek
Menzel, Marion I.
Menze, Bjoern H.
Abstract
Magnetic resonance fingerprinting (MRF) quantifies various properties simultaneously by matching measurements to a dictionary of precomputed signals. We propose to extend the MRF framework by using a database to introduce additional parameters and spatial characteristics to the dictionary. We show that, with an adequate matching technique which includes an update of selected fingerprints in parameter space, it is possible to reconstruct parametric maps, synthesize modalities, and label tissue types at the same time directly from an MRF acquisition. We compare (1) relaxation maps from a spatiotemporal dictionary against a temporal MRF dictionary, (2) synthetic diffusion metrics versus those obtained with a standard diffusion acquisition, and (3) anatomical labels generated from MRF signals to an established segmentation method, demonstrating the potential of using MRF for multiparametric brain mapping.
Keywords
Fractional Anisotropy Diffusion Weighted Imaging Mean Diffusivity Radial Diffusivity Relaxation Mapping
Date
2016
Type
Conference item
Journal
MICCAI 2016 19th International Conference on Medical Image Computing & Computer Assisted Intervention
Book
Volume
9902
Issue
Page Range
579-586
Article Number
ACU Department
Collections
Relation URI
Source URL
Event URL
Open Access Status
License
File Access
Controlled